The US announced on Thursday that Taobao Marketplace, owned by Chinese e-commerce giant Alibaba Group, has been removed from its yearly list of the world's most "notorious markets," so-called because they are rampant with pirated and counterfeit goods.Source: http://feedproxy.google.com/~r/Techcrunch/~3/tsmczElvncw/
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Generating traffic is one of the key procedures associated with internet marketing. One of, if not the most captivating web traffic technique available at the moment is Pay-Per-Click advertising or PPC for short.
Essentially, PPC is an in internet advertising model, where advertisers pay the website owner when the ad on their site is clicked.
Most businesses locate their pay-per-click advertisement campaigns on search engine pages, online directories and popular social network sites. You want it on sites that have millions of users every day, so that the PPC advertising campaign can reach its full potential.
Furthermore, the PPC advertisement is placed on pages that contain related content and keywords, because let?s be honest, having an advertisement a suit tailor is pointless when the keyword the user uses is web design. Being placed amongst closely related content allows a process called sponsored match to take place. Sponsored is when a business can efficiently target potential customers searching for their niche, these types of customer are more likely to purchase also.
PPC advertising can be set up very quickly and provides a great deal of information to measure campaign performance. You only pay for ?click-throughs? so it can be a highly cost-effective form of advertising when implemented correctly. In order for your PPC Campaign to be successful, it requires strategic thinking, cutting-edge analysis and persistent management throughout. By continually assessing and adopting your tactics you can ensure that your campaign is optimized; maximizing your return on investment.
The literature within your PPC advertisement must be accurate and effective as this is the most vital component of your PPC campaign. Clearly, the aim of the advert is to attract targeted leads, however you barely have 100 characters to do this in, therefore your ad needs to be compelling in order to attract buyers.
Listed below are a few key pointers that should help you when writing your PPC advert:
??? ?Keep your content simple.
??? ?Include only the best keywords.
??? ?If you only target a certain geographical area such as London, ensure that you specify this within your PPC advert.
??? ?If you have a time-related benefit, ensure that you mention it. This will form a sense of pressure on the viewer to buy.
All being well, PPC does pose a possible threat.
The primary determinant when it comes to the costing of your PPC advert? is based on the popularity of the key word that you are trying to use. Evidentially, the more the key word is sought after, the higher the cost of using it will be. If this is the case, it is basically impossible for a business to utilize the targeted keywords that would yield the best results for their business.
Source: http://www.ebay-success-secrets.com/the-ins-and-outs-of-pay-per-click-advertising/
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The number of options out there for iPad stylii at this point is almost crazy. But Ten One Design has always made solid ones, and the Pogo Connect also adds pressure sensitivity via Bluetooth 4.0. It's a slightly different take than others in this space, and one that benefits immensely from extremely low power consumption.Source: http://feedproxy.google.com/~r/Techcrunch/~3/rXrmqKC6L44/
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Public release date: 12-Dec-2012
Share ] Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center
SEATTLE Younger women who wait at least 15 years after their first menstrual period to give birth to their first child may reduce their risk of an aggressive form of breast cancer by up to 60 percent, according to a Fred Hutchinson Cancer Research Center study. The findings, by Christopher I. Li, M.D., Ph.D., a member of the Public Health Sciences Division at Fred Hutch, are published online in Breast Cancer Research and Treatment.
"We found that the interval between menarche and age at first live birth is inversely associated with the risk of triple-negative breast cancer," Li said. While relatively uncommon, triple-negative breast cancer is a particularly aggressive subtype of the disease that does not depend on hormones such as estrogen to grow and spread. This type of cancer, which accounts for only 10 percent to 20 percent of all breast cancers, does not express the genes for estrogen receptor (ER), progesterone receptor (PR) or HER2/neu and therefore does not respond to hormone-blocking drugs such as Tamoxifen.
The study by Li and colleagues in the Public Health Sciences and Human Biology divisions at Fred Hutch is the first to look at how the interval between first menstrual period and age at first birth is related to the risk of this particular type of breast cancer. It is also the first study to look at the relationship between reproductive factors and breast cancer risk among premenopausal women, who have a higher risk of triple-negative and HER2-overexpressing breast cancer than postmenopausal women.
The study also confirmed several previous studies that have suggested that breast-feeding confers a protective effect against triple-negative disease. "Breast-feeding is emerging as a potentially strong protective factor against one of the most aggressive forms of breast cancer," Li said.
The mechanism by which breast-feeding and delaying childbirth reduces the risk of this form of breast cancer is unclear, Li said.
Previous research has shown, however, that the risk of the most common subtype of breast cancer, ER positive, is decreased among women who've had a full-term pregnancy and have breast-fed. The reason for this, researchers believe, is that the hormones of pregnancy induce certain changes in the cellular structure of the breast that seem to make the tissue less susceptible to this type of cancer.
The study has particular implications for African-American women, who experience disproportionately high rates of triple-negative disease. While the reason for this remains largely unknown, on a population level reproductive characteristics are known to vary by race, and compared to non-Hispanic white women, African-American women are more likely to start having children at a younger age and are less likely to breast-feed, Li said.
"Our observations that delayed childbearing and breast-feeding are protective against triple-negative breast cancer suggest that variations in reproductive histories by race may to some extent explain the higher rates of triple-negative disease in African-American women," Li said.
The study involved more than 1,960 Seattle-area women between the ages of 20 and 44, 1,021 with a history of breast cancer and 941 without. Reproductive histories among women without a history of breast cancer were compared to those of women with ER-positive (781), triple-negative (180) and HER2-overexpressing (60) breast cancer.
"This is an observational study and also one of the first to focus on premenopausal breast cancer and so our results require confirmation and thus should be interpreted with some caution," Li said.
###
The National Cancer Institute and the Department of Defense Breast Cancer Research Program funded the study.
Editor's note: To obtain a copy of the Breast Cancer Research and Treatment paper, "Reproductive factors and risk of estrogen receptor positive, triple-negative, and HER2-neu overexpressing breast cancer among women 20-44 years of age," visit http://www.springerlink.com/openurl.asp?genre=article&id=doi:10.1007/s10549-012-2365-1
At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer with minimal side effects. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Private contributions are essential for enabling Fred Hutch scientists to explore novel research opportunities that lead to important medical breakthroughs. For more information visit www.fhcrc.org or follow Fred Hutch on Facebook, Twitter or YouTube.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 12-Dec-2012 Share ] Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center
SEATTLE Younger women who wait at least 15 years after their first menstrual period to give birth to their first child may reduce their risk of an aggressive form of breast cancer by up to 60 percent, according to a Fred Hutchinson Cancer Research Center study. The findings, by Christopher I. Li, M.D., Ph.D., a member of the Public Health Sciences Division at Fred Hutch, are published online in Breast Cancer Research and Treatment.
"We found that the interval between menarche and age at first live birth is inversely associated with the risk of triple-negative breast cancer," Li said. While relatively uncommon, triple-negative breast cancer is a particularly aggressive subtype of the disease that does not depend on hormones such as estrogen to grow and spread. This type of cancer, which accounts for only 10 percent to 20 percent of all breast cancers, does not express the genes for estrogen receptor (ER), progesterone receptor (PR) or HER2/neu and therefore does not respond to hormone-blocking drugs such as Tamoxifen.
The study by Li and colleagues in the Public Health Sciences and Human Biology divisions at Fred Hutch is the first to look at how the interval between first menstrual period and age at first birth is related to the risk of this particular type of breast cancer. It is also the first study to look at the relationship between reproductive factors and breast cancer risk among premenopausal women, who have a higher risk of triple-negative and HER2-overexpressing breast cancer than postmenopausal women.
The study also confirmed several previous studies that have suggested that breast-feeding confers a protective effect against triple-negative disease. "Breast-feeding is emerging as a potentially strong protective factor against one of the most aggressive forms of breast cancer," Li said.
The mechanism by which breast-feeding and delaying childbirth reduces the risk of this form of breast cancer is unclear, Li said.
Previous research has shown, however, that the risk of the most common subtype of breast cancer, ER positive, is decreased among women who've had a full-term pregnancy and have breast-fed. The reason for this, researchers believe, is that the hormones of pregnancy induce certain changes in the cellular structure of the breast that seem to make the tissue less susceptible to this type of cancer.
The study has particular implications for African-American women, who experience disproportionately high rates of triple-negative disease. While the reason for this remains largely unknown, on a population level reproductive characteristics are known to vary by race, and compared to non-Hispanic white women, African-American women are more likely to start having children at a younger age and are less likely to breast-feed, Li said.
"Our observations that delayed childbearing and breast-feeding are protective against triple-negative breast cancer suggest that variations in reproductive histories by race may to some extent explain the higher rates of triple-negative disease in African-American women," Li said.
The study involved more than 1,960 Seattle-area women between the ages of 20 and 44, 1,021 with a history of breast cancer and 941 without. Reproductive histories among women without a history of breast cancer were compared to those of women with ER-positive (781), triple-negative (180) and HER2-overexpressing (60) breast cancer.
"This is an observational study and also one of the first to focus on premenopausal breast cancer and so our results require confirmation and thus should be interpreted with some caution," Li said.
###
The National Cancer Institute and the Department of Defense Breast Cancer Research Program funded the study.
Editor's note: To obtain a copy of the Breast Cancer Research and Treatment paper, "Reproductive factors and risk of estrogen receptor positive, triple-negative, and HER2-neu overexpressing breast cancer among women 20-44 years of age," visit http://www.springerlink.com/openurl.asp?genre=article&id=doi:10.1007/s10549-012-2365-1
At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer with minimal side effects. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Private contributions are essential for enabling Fred Hutch scientists to explore novel research opportunities that lead to important medical breakthroughs. For more information visit www.fhcrc.org or follow Fred Hutch on Facebook, Twitter or YouTube.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-12/fhcr-dcm121212.php
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Nintendo may not be giving up its gaming IPs to smartphones just yet, but the Japanese gaming giant is willing to work with them if it means crosspromoting games on standalone Nintendo consoles. Take, for example, today's release of the interactive Pokémon "Pokédex," available for $2 across various iOS devices -- Nintendo clearly isn't against taking fans' money in exchange for a valuable service: information on over 640 Pokémon on-the-go ... if you buy the three upgrade packs for $5.99 apiece (!!), that is.
Support for the app extends all the way back to the aged iPhone 3GS, and through to the newest iPad (as well as the iPad Mini), so you'll be able to explore the wild world of Tepig from a vast array of iOS hardware. Of course, much of this could be meaningless to you if you grabbed the free version previously available on Nintendo's 3DS, but then you put it off, didn't you? And now here we are.
Continue reading Nintendo on iOS? Pok?dex arrives on iOS in the US and Europe, costs $2
Filed under: Cellphones, Gaming, Handhelds, Tablets, Software, Mobile, Nintendo
Source: iTunes
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/wCJZpRGyfZ4/
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KIGALI (Reuters) - Rwanda's year-on-year urban inflation fell to 4.55 percent in November, thanks to a drop in prices of food and non-alcoholic beverages, the statistics office said on Monday.
Prices of fish, vegetables and health services fell during the month. The landlocked central African nation's economic growth rose to 9.4 percent in the fiscal year ended last June from 7.4 percent previously.
But economic growth prospects could wane if donors, who suspended some aid over Rwanda's alleged support for rebels in the neighbouring Democratic Republic of Congo, fail to reinstate the aid soon, Finance Minister John Rwangombwa said.
Rwangombwa told a conference in Kigali last week that Rwanda may have to cut its 2013 economic growth forecast if $240 million in aid remains frozen.
Source: http://news.yahoo.com/rwanda-urban-inflation-falls-4-55-pct-november-112203294--business.html
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FILE -In this June 17, 2010 file photo, former South African President, Nelson Mandela leaves the chapel after attending the funeral of his great-granddaughter Zenani Mandela in Johannesburg, South Africa. South African President Jacob Zuma says that former President Nelson Mandela has been admitted to hospital in Pretoria to undergo tests. Zuma issued a statement Saturday, Dec. 8, 2012 saying that Mandela is "doing well and there is no cause for alarm." (AP Photo/Siphiwe Sibeko, Pool, File)
FILE -In this June 17, 2010 file photo, former South African President, Nelson Mandela leaves the chapel after attending the funeral of his great-granddaughter Zenani Mandela in Johannesburg, South Africa. South African President Jacob Zuma says that former President Nelson Mandela has been admitted to hospital in Pretoria to undergo tests. Zuma issued a statement Saturday, Dec. 8, 2012 saying that Mandela is "doing well and there is no cause for alarm." (AP Photo/Siphiwe Sibeko, Pool, File)
FILE - In this Wednesday, July 18, 2012 file photo, former South African President Nelson Mandela as he celebrates his birthday with family in Qunu, South Africa. South African President Jacob Zuma says that former President Nelson Mandela has been admitted to hospital in Pretoria to undergo tests. Zuma issued a statement Saturday, Dec. 8, 2012 saying that Mandela is "doing well and there is no cause for alarm." (AP Photo/Schalk van Zuydam, File)
JOHANNESBURG (AP) ? South Africa's former President Nelson Mandela was admitted to a military hospital Saturday for medical tests, though the nation's president told the public there was "no cause for alarm" over the 94-year-old icon's health.
The statement issued by President Jacob Zuma's spokesman said that Mandela was doing well and was receiving medical care "which is consistent for his age." The statement offered no other details.
Mandela, who spent 27 years in prison for fighting racist white rule, became South Africa's first black president in 1994 and served one five-year term. He later retired from public life to live in his village of Qunu, and last made a public appearance when his country hosted the 2010 World Cup soccer tournament.
"We wish Madiba all the best," Zuma said in the statement, using Mandela's clan name. "The medical team is assured of our support as they look after and ensure the comfort of our beloved founding president of a free and democratic South Africa."
While the government sought to reassure South Africans about Mandela's health, he remains viewed as a father figure to many in this nation of 50 million people. Each hospital trip raises the same worries about the increasingly frail former leader of the African National Congress ? that the man who helped bring the nation together is slowly fading away.
In February, Mandela spent a night in a hospital for a minor diagnostic surgery to determine the cause of an abdominal complaint. In January 2011, however, Mandela was admitted to a Johannesburg hospital for what officials initially described as tests but what turned out to be an acute respiratory infection. He was discharged days later.
Mandela contracted tuberculosis during his years in prison. He also had surgery for an enlarged prostate gland in 1985.
While Zuma's statement offered no further details about who would provide medical attention for Mandela, the nation's military has taken over caring for the aging leader since the 2011 respiratory infection. At 1 Military Hospital in Pretoria on Saturday night, the facility that previously cared for Mandela in February, everything appeared calm, without any additional security present.
Mac Maharaj, a presidential spokesman, declined to say whether Mandela had been flown by the military from Qunu to Pretoria. He also declined to say what the tests were for.
"It's quite normal at his age to be going through those tests," Maharaj told The Associated Press.
Mandela's hospitalization comes just days after the crash of a military aircraft flying on an unknown mission near Mandela's rural home in which all 11 onboard were killed.
The plane was flying to a military air base in Mthatha, which is about 30 kilometers (17 miles) north of Qunu. Military officials declined to say whether those on board had any part in caring for Mandela.
___
Associated Press writers Thomas Phakane in Pretoria, South Africa, and Andrew Meldrum in Johannesburg contributed to this report.
___
Jon Gambrell can be reached at www.twitter.com/jongambrellAP .
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Source: http://feeds.celebritybabies.com/~r/celebrity-babies/~3/k3VEVBct_tY/
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Tennis players, Roger Federer, of Switzerland, and Maria Sharapova of Russia hold a press conference to promote the Gillette Federer Tour, in Sao Paulo, Brazil, Thursday, Dec. 6, 2012. Federer will take on Brazilian Thomaz Bellucci in an exhibition match Thursday evening, Sharapova and Danish tennis star Caroline Wozniacki are scheduled for a Friday match. (AP Photo/Andre Penner)
Tennis players, Roger Federer, of Switzerland, and Maria Sharapova of Russia hold a press conference to promote the Gillette Federer Tour, in Sao Paulo, Brazil, Thursday, Dec. 6, 2012. Federer will take on Brazilian Thomaz Bellucci in an exhibition match Thursday evening, Sharapova and Danish tennis star Caroline Wozniacki are scheduled for a Friday match. (AP Photo/Andre Penner)
Tennis player Roger Federer, of Switzerland, shaves during a press conference to promote the Gillete Federer Tour, in Sao Paulo, Brazil, Thursday, Dec. 6, 2012. Federer will take on Brazilian Thomaz Bellucci in an exhibition match Thursday evening. (AP Photo/Andre Penner)
SAO PAULO (AP) ? Roger Federer says he won't play as often in the next few years but wants to compete in the 2016 Olympics in Rio de Janeiro.
The 31-year-old Swiss star intends to be more mindful about the tournaments he plays to make sure he can keep playing at a high level.
"I have to make sure that I take care of my schedule, of my body, of my mind," he said Thursday. "Hopefully, I can still stay on tour for many more years and hopefully play the Olympics here in three and a half years or so, so I have to look far ahead and not just the next six months."
The winner of 17 Grand Slams is in Sao Paulo for exhibition matches involving Maria Sharapova, Victoria Azarenka, Serena Williams, Caroline Wozniacki, Jo-Wilfried Tsonga, Tommy Robredo, Tommy Haas and Thomaz Bellucci. The Bryan brothers, Bob and Mike, are also participating. Federer plays Bellucci, Brazil's top-ranked player, on Thursday.
Federer has competed in four Olympics, winning a doubles gold in 2008 and a singles silver this year. He would love to make it to the Rio Games.
"There is a lot of passion for sports here," he said. "It's a hot place to play tennis right now."
Federer, who ended the season ranked No. 2, said this year was difficult because of additional commitments that kept him from practice and his family.
"I've played a lot of tennis. It's been a big challenge, especially with the Olympics and the Davis Cup this year," he said. "I found my way back to world No. 1 and it took a lot of sacrifices. I'd like to be home a little bit more often and in a relaxed fashion."
Still, he said it was a rewarding season.
"I'm very happy that I'm still playing at a very high level," said Federer, who won six titles this year, including Wimbledon. "I had one of my best years on tour this year, and one of the most emotional ones, of course. Next year tournament victories will probably be more important than the rankings, that's why I need to make sure I practice a lot next year."
Federer played 19 tournaments in 2012, two more than top-ranked Novak Djokovic. No. 3 Andy Murray also played 19 and Rafael Nadal, nursing a knee injury, played only 11.
"I'm not going to play 25 tournaments, but every tournament that I will be playing I'll be emotionally attached to it because I either won there before or because I've been there many times or because I love the city or the country and the fans," he said. "Today I've reached a point in my life that I can pick and choose where I want to play and how much I want to play."
One of the tournaments he left off his 2013 schedule was Miami, the Masters event in March he has played since 1999 and won twice.
"Miami was a tough decision for me," he said. "But I have to take some time off, first of all, but most importantly, I need to practice. This year I couldn't practice at all. Something had to go in the calendar and that was Miami, unfortunately."
Federer said he thinks he will need two Grand Slams and five to eight titles in other tournaments to get back to No. 1.
"It's difficult," he said. "But I'm happy to set that challenge and I'll give everything I have."
___
Follow Tales Azzoni at http://twitter.com/tazzoni
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WASHINGTON (AP) ? Sen. John Kerry says Secretary of State Hillary Rodham Clinton has agreed to testify before the Senate Foreign Relations Committee about an independent report on the deadly Sept. 11 attack on the U.S. diplomatic mission in Libya.
In a letter Friday to the panel's members, Kerry indicated that the report from the accountability review board headed by retired diplomat Thomas Pickering is imminent. The Massachusetts Democrat and committee chairman says he's asked that Pickering and retired Adm. Mike Mullen appear before the committee before Clinton. Mullen, the former chairman of the Joint Chiefs of Staff, is a member of the review board.
The attack on the consulate in Benghazi killed U.S. Ambassador Chris Stevens and three other Americans.
Clinton has also agreed to testify before the House Foreign Affairs Committee.
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Britain's Lord Justice Brian Leveson pauses as he delivers a statement following the release of the Leveson Inquiry report at the Queen Elizabeth II Centre, London, Thursday, Nov. 29, 2012. After a yearlong inquiry full of sensational testimony, Lord Justice Leveson released his report Thursday into the culture and practices of the British press and his recommendations for future regulation to prevent phone hacking, data theft, bribery and other abuses. (AP Photo/Dan Kitwood, Pool)
Britain's Lord Justice Brian Leveson pauses as he delivers a statement following the release of the Leveson Inquiry report at the Queen Elizabeth II Centre, London, Thursday, Nov. 29, 2012. After a yearlong inquiry full of sensational testimony, Lord Justice Leveson released his report Thursday into the culture and practices of the British press and his recommendations for future regulation to prevent phone hacking, data theft, bribery and other abuses. (AP Photo/Dan Kitwood, Pool)
A man carries copies of the Leveson Inquiry report as he leaves the Queen Elizabeth II Conference Centre where Lord Justice Brian Leveson released his report, after a year long inquiry, into the culture and practices of the British press and his recommendations for future regulation to prevent phone hacking, data theft, bribery and other abuses, London, Thursday, Nov. 29, 2012. (AP Photo/Kirsty Wigglesworth)
Britain's Lord Justice Brian Leveson delivers a statement following the release of the Leveson Inquiry report at the Queen Elizabeth II Centre, London, Thursday, Nov. 29, 2012. After a yearlong inquiry full of sensational testimony, Lord Justice Leveson released his report Thursday into the culture and practices of the British press and his recommendations for future regulation to prevent phone hacking, data theft, bribery and other abuses. (AP Photo/Dan Kitwood, Pool)
Britain's Lord Justice Brian Leveson, center back, delivers a statement following the release of the Leveson Inquiry report at the Queen Elizabeth II Centre, London, Thursday, Nov. 29, 2012. After a yearlong inquiry full of sensational testimony, Lord Justice Leveson released his report Thursday into the culture and practices of the British press and his recommendations for future regulation to prevent phone hacking, data theft, bribery and other abuses. (AP Photo/Dan Kitwood, Pool)
Britain's Lord Justice Brian Leveson delivers a statement following the release of the Leveson Inquiry report at the Queen Elizabeth II Centre, London, Thursday, Nov. 29, 2012. After a yearlong inquiry full of sensational testimony, Lord Justice Leveson released his report Thursday into the culture and practices of the British press and his recommendations for future regulation to prevent phone hacking, data theft, bribery and other abuses. (AP Photo/Dan Kitwood, Pool)
LONDON (AP) ? Britain's unruly newspapers should be regulated by an independent body dominated by non-journalists with the power to levy steep fines, a judge said Thursday in a report that pleased victims of tabloid intrusion but left editors worrying about creeping state control of the country's fiercely independent press.
Prime Minister David Cameron echoed concerns about government interference, expressing misgivings about a key recommendation of the report ? that the new regulator be enshrined in law. He called on the much criticized press to show it could control itself by implementing the judge's proposals quickly ? and without political involvement.
"I'm proud of the fact that we've managed to survive hundreds of years without state regulation," he said.
Lord Justice Brian Leveson issued his 2,000-page report at the end of a media ethics inquiry triggered by a scandal over tabloid phone hacking that expanded to engulf senior figures in politics, the police and Rupert Murdoch's media empire.
His key recommendation was to create a new print media regulator, which he said should be established in law to prevent more people being hurt by "outrageous" press behavior that had "wreaked havoc with the lives of innocent people whose rights and liberties have been disdained."
Cameron, under intense pressure from both sides of an issue that has divided his own Conservative Party, welcomed Leveson's proposal for a new regulator and said "the status quo is not an option."
But he said that asking legislators to enshrine it in law meant "crossing the Rubicon of writing elements of press regulation into the law of the land."
"I believe that we should be wary of any legislation that has the potential to infringe free speech and a free press," Cameron told lawmakers in the House of Commons. "In this House which has been a bulwark of democracy for centuries, we should think very, very carefully before crossing this line."
Leveson insisted that politicians and the government should play no role in regulating the press, which should be done by a new body with much stronger powers than the current Press Complaints Commission.
But the judge said it was "essential that there should be legislation to underpin the independent self-regulatory system."
He said the new body should be composed of members of the public including former journalists and academics ? but no more than one serving editor, and no politicians. It should have the power to rule on complaints, demand prominent corrections in newspapers and to levy fines of up to 1 million pounds ($1.6 million), though it would have no power to prevent material being published.
Membership would be voluntary, but newspapers would be encouraged to join in part to stave off expensive lawsuits ? the regulator would handle complaints that currently end up in court.
The proposal is similar to the system operating in Ireland, where a press council and ombudsman were set up in 2008 to make the print media more publicly accountable.
Critics of the tabloid press generally backed Leveson's findings.
"I welcome Lord Leveson's report and hope it will mark the start of a new era for our press in which it treats those in the news responsibly, with care and consideration," said Kate McCann, who was the subject of intense press interest after her 3-year-old daughter Madeleine disappeared during a holiday in Portugal in 2007.
Brian Cathcart of the group Hacked Off, which campaigns for victims of press intrusion, said Leveson had produced "a workable, proportionate and reasonable solution to the problems of press abuse."
He said Cameron's "failure to accept the full recommendations of the report is unfortunate and regrettable."
Cameron set up the Leveson inquiry after revelations of illegal eavesdropping by Rupert Murdoch's now-defunct News of the World tabloid sparked a criminal investigation and a wave of public revulsion.
The furor erupted in 2011 when it was revealed that the News of the World had eavesdropped on the mobile phone voicemails of slain schoolgirl Milly Dowler while police were searching for the 13-year-old.
Murdoch shut down the 168-year-old newspaper in July 2011. His U.K. newspaper company, News International, has paid millions in damages to dozens of hacking victims, and faces dozens more lawsuits from celebrities, politicians, athletes and crime victims whose voicemails were hacked in the paper's quest for scoops.
News International chief executive Tom Mockridge said the company was "keen to play our full part, with others in our industry, in creating a new body that commands the confidence of the public."
"We believe that this can be achieved without statutory regulation ? and welcome the prime minister's rejection of that proposal."
Leveson's 4 million pound ($6.4 million) inquiry heard evidence from more than 300 witnesses during months of hearings that provided a dramatic, sometimes comic and often poignant window on the workings of the media. Witnesses ranged from celebrities such as Harry Potter author J.K. Rowling and Hugh Grant ? who both complained of intrusive treatment ? to the parents of Dowler, who described how learning that their daughter's voicemail had been accessed had given them false hope that she was alive.
Leveson said that the ongoing criminal investigation constrained him from accusing other newspapers of illegal behavior, but concluded there was a subculture of unethical behavior "within some parts of some titles."
While many editors have denied knowing about phone hacking, Leveson said it "was far more than a covert, secret activity, known to nobody save one or two practitioners of the 'dark arts.'"
He said newspapers had been guilty of "recklessness in prioritizing sensational stories almost irrespective of the harm the stories may cause."
"In each case, the impact has been real and, in some cases, devastating," the judge said.
The hacking scandal has rocked Britain's press, political and police establishments, who were revealed to enjoy an often cozy relationship in which drinks, dinners and sometimes money were traded for influence and information.
Several senior police officers resigned over the failure aggressively to pursue an investigation of phone hacking at the News of the World in 2007. But Leveson said that "the inquiry has not unearthed extensive evidence of police corruption."
Leveson said over the past three decades, political parties "have had or developed too close a relationship with the press in a way which has not been in the public interest."
Those relationships reached right up to the prime minister's door. Former Murdoch editors and journalists charged with phone hacking, police bribery or other wrongdoing include Cameron's former spokesman, Andy Coulson, and ex-News of the World editor Rebekah Brooks, a friend of the prime minister.
Leveson acquitted senior politicians of wrongdoing, but recommended that political parties publish statements "setting out, for the public, an explanation of the approach they propose to take as a matter of party policy in conducting relationships with the press."
Cameron, who is tainted by his own ties to prominent figures in the scandal, said he accepted that proposal.
But politicians remained far apart on the broader issue of how, or whether, to regulate the press.
Cameron was holding talks Thursday with leaders of the other main parties in an attempt to thrash out agreement.
He faced a battle. Deputy Prime Minister Nick Clegg, leader of junior government partner the Liberal Democrats, differed from Cameron in backing the call for a new regulator established in law.
"We owe it to the victims of these scandals, who have already waited too long for us to do the right thing," he said.
Analysts say that it was possible for the coalition government's two parties to join forces and push through a version of the recommended legal changes.
But Steven Barnett, a communications professor at the University of Westminster, said that if that does not happen, he would not trust the British press to set up a truly independent regulator.
"One possibility is that in the end (the report) has no effect whatsoever," Barnett said. "The press can make some noises about regulating themselves. But in the end they will want to control themselves in ways that Leveson himself said was unacceptable."
___
Online: http://www.levesoninquiry.org.uk/
Jill Lawless can be reached at http://Twitter.com/JillLawless
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Microsoft brought its SmartGlass Xbox 360 second screen app to Android last month, however official support was limited to smartphones. While many found that sideloading got the app running on their other devices, an update today has officially added support for tablets of the 7-inch variety. There's also fixes for specific crashes tied to the achievements and settings screens, but not much else. If you've been waiting to bring your Nexus 7 along as GPS in Forza Horizon or control tracks in Dance Central 3, hit the source link to install the app straight from Google Play.
Filed under: Gaming, Tablets, Microsoft
Source: Google Play
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/KMV-zrOLl8c/
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William West / AFP - Getty Images
A swimmer stops short of a red algae bloom at Sydney's Clovelly Beach on Tuesday. Clovelly and Bondi beaches were closed to swimmers.
Sydney's iconic Bondi Beach and Clovelly Beach were closed to swimmers on Tuesday as a red algae bloom drifted close to shore, Agence France-Presse reports.
While the red algae, known as Noctiluca scintillans or sea sparkle, has no toxic effects, people are still advised to avoid swimming in areas with discolored water because the algae, which can be high in ammonia, can cause skin irritation.?
"It has got quite a fishy smell to it,"?lifeguard Bruce Hopkins told?the Australian Associated Press.?"It can irritate some people's skin but generally not much more than that."
William West / AFP - Getty Images
A boy walks along Sydney's Clovelly Beach on Tuesday.
William West / AFP - Getty Images
A seagull stands in a red algae bloom at Sydney's Clovelly Beach on Tuesday.
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ScienceDaily (Nov. 23, 2012) ? Johns Hopkins researchers have uncovered a protein "partner" commonly used by breast cancer cells to unlock genes needed for spreading the disease around the body. A report on the discovery, published November 5 on the website of the Proceedings of the National Academy of Sciences, details how some tumors get the tools they need to metastasize.
"We've identified a protein that wasn't known before to be involved in breast cancer progression," says Gregg Semenza, M.D., Ph.D., the C. Michael Armstrong Professor of Medicine at the Johns Hopkins University School of Medicine and director of the Vascular Program at Hopkins' Institute for Cell Engineering. "The protein JMJD2C is the key that opens up a whole suite of genes needed for tumors to grow and metastasize, so it represents a potential target for cancer drug development."
Semenza and his colleagues made their finding when they traced the activity of HIF-1, a protein known to switch on hundreds of genes involved in development, red blood cell production, and metabolism in normal cells. Previous studies had shown that HIF-1 could also be hijacked to switch on genes needed to make breast tumors more malignant.
Would-be tumor cells face a host of challenges as they make the transition from working with their host to working against it, such as the need to evade the immune system and to produce more cancer cells, explains Weibo Luo, Ph.D., an instructor in the Institute for Cell Engineering and Department of Biological Chemistry who led the project. All of these efforts require switching on the right genes for the job.
To learn more about how HIF-1 works, the researchers tested a range of human proteins to see whether they would interact with HIF-1. They then sifted through the 200 resulting hits, looking for proteins involved in chemical changes to sections of DNA that determine whether or not the genes they contain are available for use. "In order for HIF-1 to switch genes on, they have to be available, but many of the genes HIF-1 activates are normally locked down in mature cells," explains Luo. "So we thought HIF-1 must have a partner that can do the unlocking."
That partner turned out to be JMJD2C, Luo says. Delving deeper, the researchers found that HIF-1 switches on the JMJD2C gene, stimulating production of the protein. HIF-1's presence also enables JMJD2C to bind to DNA at other HIF-1 target genes, then loosen those DNA sections, enabling more HIF-1 to bind to the same sites and activate the target genes.
To test the implications of their discovery, the research team injected mice with breast cancer cells in which the JMJD2C protein was not produced. Tumors with depleted JMJD2C were much less likely to grow and metastasize to the lungs, confirming the protein's role in breast cancer progression, says Luo.
"Active HIF proteins have been found in many types of tumors, so the implications of this finding go beyond breast cancer," says Luo. "JMJD2C is both an important piece of the puzzle of how tumors metastasize, and a potential target for anti-cancer therapy." Other authors of the research report are Ryan Chang, Jun Zhong, Ph.D., and Akhilesh Pandey, M.D., Ph.D., all of the Johns Hopkins University School of Medicine.
This work was supported by grants from the National Heart, Lung, and Blood Institute (contracts N01-HV28180 and HHS-N268201000032C), and by funds from the Johns Hopkins Institute for Cell Engineering.
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/2nYvEp2kt_g/121124090511.htm
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Whether you're going to Boston, Massachusetts for a company trip, to tour the colleges in the region, or simply to view the fall foliage, Boston car hire has dealt with every little thing.
Source: http://travel-leisure-updates.blogspot.com/2012/11/car-hire-for-safer-travel.html
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In this Thursday, Oct. 9, 2008 photo, actor Larry Hagman listens to a reporter's question while visiting the Southfork Ranch in Parker, Texas, made famous in the television show "Dallas." Actor Larry Hagman, who for more than a decade played villainous patriarch JR Ewing in the TV soap Dallas, has died at the age of 81, his family said Saturday Nov. 24, 2012(AP Photo/Tony Gutierrez)
In this Thursday, Oct. 9, 2008 photo, actor Larry Hagman listens to a reporter's question while visiting the Southfork Ranch in Parker, Texas, made famous in the television show "Dallas." Actor Larry Hagman, who for more than a decade played villainous patriarch JR Ewing in the TV soap Dallas, has died at the age of 81, his family said Saturday Nov. 24, 2012(AP Photo/Tony Gutierrez)
This 1981 file photo provided by CBS shows Larry Hagman in character as J.R. Ewing in the television series "Dallas." Actor Larry Hagman, who for more than a decade played villainous patriarch JR Ewing in the TV soap Dallas, has died at the age of 81, his family said Saturday Nov. 24, 2012. (AP Photo/CBS, file)
FILE - This 1967 file photo shows Barbara Eden, left, and Larry Hagman in a scene from the television show "I Dream of Jeannie." Actor Larry Hagman, who for more than a decade played villainous patriarch JR Ewing in the TV soap Dallas, has died at the age of 81, his family said Saturday Nov. 24, 2012. (AP Photo/NBC, file)
FILE - In this Wednesday, Feb. 19, 2003 file photo, actor Larry Hagman sits in front of a poster of himself during a news conference in Berlin during a tour to promote the German translation of his autobiography. Actor Larry Hagman, who for more than a decade played villainous patriarch JR Ewing in the TV soap Dallas, has died at the age of 81, his family said Saturday Nov. 24, 2012. (AP Photo/Markus Schreiber)
FILE - In this Nov. 4, 2011 file photo, actor Larry Hagman pauses during an interview on location during the filming for the upcoming new television show "Dallas" in Dallas. Actor Larry Hagman, who for more than a decade played villainous patriarch JR Ewing in the TV soap Dallas, has died at the age of 81, his family said Saturday Nov. 24, 2012. (AP Photo/Tony Gutierrez, File)
J.R. Ewing was a business cheat, faithless husband and bottomless well of corruption. Yet with his sparkling grin, Larry Hagman masterfully created the charmingly loathsome oil baron ? and coaxed forth a Texas-size gusher of ratings ? on television's long-running and hugely successful nighttime soap, "Dallas."
Although he first gained fame as nice guy Capt. Tony Nelson on the fluffy 1965-70 NBC comedy "I Dream of Jeannie," Hagman earned his greatest stardom with J.R. The CBS serial drama about the Ewing family and those in their orbit aired from April 1978 to May 1991, and broke viewing records with its "Who shot J.R.?" 1980 cliffhanger that left unclear if Hagman's character was dead.
The actor, who returned as J.R. in a new edition of "Dallas" this year, had a long history of health problems and died Friday due to complications from his battle with cancer, his family said.
"Larry was back in his beloved hometown of Dallas, re-enacting the iconic role he loved the most. Larry's family and closest friends had joined him in Dallas for the Thanksgiving holiday," the family said in a statement that was provided to The Associated Press by Warner Bros., producer of the show.
The 81-year-old actor was surrounded by friends and family before he passed peacefully, "just as he'd wished for," the statement said.
Linda Gray, his on-screen wife and later ex-wife in the original series and the sequel, was among those with Hagman in his final moments in a Dallas hospital, said her publicist, Jeffrey Lane.
"He brought joy to everyone he knew. He was creative, generous, funny, loving and talented, and I will miss him enormously. He was an original and lived life to the fullest," the actress said.
Years before "Dallas," Hagman had gained TV fame on "I Dream of Jeannie," in which he played an astronaut whose life is disrupted when he finds a comely genie, portrayed by Barbara Eden, and takes her home to live with him.
Eden recalled late Friday shooting the series' pilot "in the frigid cold" on a Malibu beach.
"From that day, for five more years, Larry was the center of so many fun, wild and sometimes crazy times. And in retrospect, memorable moments that will remain in my heart forever," Eden said.
Hagman also starred in two short-lived sitcoms, "The Good Life" (NBC, 1971-72) and "Here We Go Again" (ABC, 1973). His film work included well-regarded performances in "The Group," ''Harry and Tonto" and "Primary Colors."
But it was Hagman's masterful portrayal of J.R. that brought him the most fame. And the "Who shot J.R.?" story twist fueled international speculation and millions of dollars in betting-parlor wagers. It also helped give the series a place in ratings history.
When the answer was revealed in a November 1980 episode, an average 41 million U.S. viewers tuned in to make "Dallas" one of the most-watched entertainment shows of all time, trailing only the "MASH" finale in 1983 with 50 million viewers.
It was J.R.'s sister-in-law, Kristin (Mary Crosby) who plugged him ? he had made her pregnant, then threatened to frame her as a prostitute unless she left town ? but others had equal motivation.
Hagman played Ewing as a bottomless well of corruption with a charming grin: a business cheat and a faithless husband who tried to get his alcoholic wife, Sue Ellen (Gray), institutionalized.
"I know what I want on J.R.'s tombstone," Hagman said in 1988. "It should say: 'Here lies upright citizen J.R. Ewing. This is the only deal he ever lost.'"
On Friday night, Victoria Principal, who co-starred in the original series, recalled Hagman as "bigger than life, on-screen and off. He is unforgettable, and irreplaceable, to millions of fans around the world, and in the hearts of each of us, who was lucky enough to know and love him."
Ten episodes of the new edition of "Dallas" aired this past summer and proved a hit for TNT. Filming was in progress on the sixth episode of season two, which is set to begin airing Jan. 28, the network said.
There was no immediate comment from Warner or TNT on how the series would deal with Hagman's loss.
In 2006, he did a guest shot on FX's drama series "Nip/Tuck," playing a macho business mogul. He also got new exposure in recent years with the DVD releases of "I Dream of Jeannie" and "Dallas."
The Fort Worth, Texas, native was the son of singer-actress Mary Martin, who starred in such classics as "South Pacific" and "Peter Pan." Martin was still in her teens when he was born in 1931 during her marriage to attorney Ben Hagman.
As a youngster, Hagman gained a reputation for mischief-making as he was bumped from one private school to another. He made a stab at New York theater in the early 1950s, then served in the Air Force from 1952-56 in England.
While there, he met and married young Swedish designer Maj Axelsson. The couple had two children, Preston and Heidi, and were longtime residents of the Malibu beach colony that is home to many celebrities.
Hagman returned to acting and found work in the theater and in such TV series as "The U.S. Steel Hour," ''The Defenders" and "Sea Hunt." His first continuing role was as lawyer Ed Gibson on the daytime serial "The Edge of Night" (1961-63).
He called his 2001 memoir "Hello Darlin': Tall (and Absolutely True) Tales about My Life."
"I didn't put anything in that I thought was going to hurt someone or compromise them in any way," he told The Associated Press at the time.
Hagman was diagnosed in 1992 with cirrhosis of the liver and acknowledged that he had drank heavily for years. In 1995, a malignant tumor was discovered on his liver and he underwent a transplant.
After his transplant, he became an advocate for organ donation and volunteered at a hospital to help frightened patients.
"I counsel, encourage, meet them when they come in for their operations, and after," he said in 1996. "I try to offer some solace, like 'Don't be afraid, it will be a little uncomfortable for a brief time, but you'll be OK.' "
He also was an anti-smoking activist who took part in "Great American Smoke-Out" campaigns.
Funeral plans were not immediately announced.
"I can honestly say that we've lost not just a great actor, not just a television icon, but an element of pure Americana," Eden said in her statement Friday night. "Goodbye, Larry. There was no one like you before and there will never be anyone like you again."
___
Associated Press writers Erin Gartner in Chicago and Shaya Mohajer in Los Angeles, and AP Television Writer Frazier Moore in New York contributed to this report.
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While there are plenty of deals and discounts to be had on TVs, phones, laptops and other tech products, camera-wise, there aren't a lot of reasons to wait in line until midnight after Thanksgiving dinner. That's because the year's best cameras ? many of which are rounded up here ? simply aren't subject to fire-sale pricing.
Source: http://www.msnbc.msn.com/id/3036697/vp/49903755#49903755
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